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  5. Tocris Bioscience™ TAK 375

Tocris Bioscience™ TAK 375
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Product Code. 18728586
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18728586

Brand: Tocris Bioscience™ 6777/10

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This item is not returnable. View return policy

Description

Very high affinity and selective melatonin receptor agonist

TAK 375 is a very high affinity and selective melatonin agonist (Ki values are 14 and 112 pM for human MT1 and MT2, respectively). Selective for human MT1 and MT2 over hamster MT3 and a range of other targets including benzodiazepine, opiate and dopamine receptors, ion channels and transporters. Accelerates return to normal circadian rhythm in rats after phase shift, without affecting learning and memory. Also reduces infarct size in rat heart in vitro post ischemia-reperfusion.
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Specifications

Synonym Ramelteon
Quantity 10 mg
Molecular Formula C16H21NO2
Formula Weight 259.34
Product Type Agonist
Purity 98%
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