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STAT6 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA534814
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: HepG2, Solitary Fibrous Tumor. Predicted reactivity: Mouse (80%), Rat (80%), Pig (90%), Rhesus Monkey (96%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.Specifications
| STAT6 | |
| Polyclonal | |
| Unconjugated | |
| STAT6 | |
| 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 20852, 6778 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.22 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P42226, P52633 | |
| STAT6 | |
| Recombinant fragment corresponding to a region within amino acids 1 and 319 of STAT6 (Uniprot ID#P42226) | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |