Staphylococcus Enterotoxin A Monoclonal Antibody (J98J), Invitrogen™

Description

The MA1-7481 antibody reacts with Staphylococcus Enterotoxin toxin A probe in bacterial and infected tissue samples. See related products for paired antibody. MA1-7481 has been successfully used in ELISA applications. The MA1-7481 antibody was raised against Staphylococcus Toxin A.

MA1-74347 recognises Staphylococcus aureus enterotoxin type A. Staphylococcus aureus produces several different types of enterotoxins (SE’s). The SE’s are short, soluble proteins that are highly stable and resistant to most proteolytic enzymes. They belong to a family of pyrogenic toxins and as such cause an increase in body temperature, immunosuppression and non-specific T-cell proliferation. These activities are referred to as superantigen activity and results from the interaction of SE’s with T-cell antigen receptors and the major histocompatibility complex (MHC) on antigen presenting cells. In addition to their superantigen activity, SE’s are also emetics (they cause vomiting). The SE’s are important in food poisoning. Enterotoxin A is one of the SE’s most commonly identified in clinical isolates. MA1-74347 may be used as a capture antibody in ELISA assays for S. aureus enterotoxin A in combination with MCA2848 as a detection agent.