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STEMCELL Technologies Sinefungin

Product Code. 17110282
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Quantity:
1 mg
Unit Size:
1mg
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Product Code. 17110282

Brand: STEMCELL Technologies 73812

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Description

Epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)

  • Sinefungin is a DNA methyltransferase (DNMT) inhibitor (IC50 = 0.1 - 20 μM; Copeland et al.) and an analog of the methyl donor S-adenosyl-L-methionine (SAM; Nolan; Horiuchi et al.)
  • Antiparasitic activity against malarial, trypanosomal, and leishmanial species (Nolan; Trager et al.; Dube et al.)
  • Inhibits Newcastle disease and vaccinia virus multiplication (Pugh et al.)
  • Inhibits pneumococcal biofilm growth in vitro and colonization in an in vivo rat model (Yadav et al.)

Specifications

CAS 58944-73-3
Synonym A 9145; Antibiotic 32232RP; Antibiotic A 9145; RP 32232
Quantity 1 mg
Molecular Formula C15H23N7O5
Purity ≥95%
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