missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 30241026

Tocris Bioscience™ SB 24011

Product Code. 30241026
Click to view available options
:
5 mg
This item is not returnable. View return policy

Product Code. 30241026

Brand: Tocris Bioscience™ 8010/5

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Inhibitor of STING-TRIM29 interaction; increases cellular STING levels

SB 24011 is an inhibitor of STING-TRIM29 interaction (IC50 = 3.85 μM in vitro). SB 24011 binds to STING and inhibits TRIM29-E3 ligase interaction to increase cellular STING levels. In syngeneic mouse models, SB 24011 dose-dependently reduces CT26 and B16F10 tumor volumes when co-admistered with cGAMP .
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 4-[(2R)-3,4-Dihydro-4-[(4-hydroxyphenyl)methyl]-5-[(4-methoxyphenyl)methyl]-2-(1-methylethyl)-3-oxo-1(2H)-pyrazinyl]-3-nitro-N-[[(2S)-tetrahydro-2-furanyl]methyl]benzamide
CAS 1497415-41-4
Quantity 5 mg
Target Protein Dimerizers
Molecular Formula C34H38N4O7
Physical Form Solid
Color Orange
Product Type Bioactive Small Molecule
Purity 0.98
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.