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ACROBiosystems Rhesus macaque OX40 Ligand / TNFSF4 Protein, Mouse IgG2a Fc Tag, low endotoxin

low endotoxin

Brand:  ACROBiosystems OXL-R5259-100UG

Additional Details : Weight : 0.00001kg

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Product Code. 15817427

  • 353.08€ / 100µg


Estimated Shipment: 28-10-2021
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Description

Description

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.

This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 42.5 kDa. The protein migrates as 47-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

XP_017808006.1
HEK293
Rhesus macaque
42.5 kDa
100 µg
Gln 51 - Leu 183
OX40L,TNFSF4,CD252,Glycoprotein Gp34,TXGP1,CD134 ligand,CD134L
Unconjugated
50 mM Tris, 100 mM Glycine, pH7.5
Less than 0.1 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>90% as determined by SDS-PAGE
Rhesus macaque O x 40 Ligand, Mouse IgG2a Fc Tag, low endotoxin (OXL-R5259) is expressed from human 293 cells (HEK293). It contains AA Gln 51 - Leu 183 (Accession # F7FL80-1).
-20°C
OX40 Ligand
Mouse IgG Fc Tag
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