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DiscoverX Ready-to-Assay™ OT Oxytocin Receptor Frozen Cells

Product Code. 17375159
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
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17375159 2 Vials of Cells 2 ampoules
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Product Code. 17375159 Supplier DiscoverX Supplier No. HTS090RTA

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Description

The Ready-to-Assay™ OT Oxytocin Receptor Frozen Cells measure OXTR (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ OT Oxytocin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. oxytocin) based activation of OXTR GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress OXTR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of OXTR , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry OT
For Use With (Application) Frozen Cells
Primary Agonist oxytocin
Quantity 2 Vials of Cells
Target Entry OXTR
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