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DiscoverX Ready-to-Assay™ CB1 Cannabinoid Receptor Frozen Cells

Product Code. 17394989
Encompass
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17394989

Brand: DiscoverX HTS019RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ CB1 Cannabinoid Receptor Frozen Cells measure CNR1 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ CB1 Cannabinoid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. cannabinoids, CP 55,940) based activation of CNR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress CNR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CNR1 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry CB1
For Use With (Application) Frozen Cells
Primary Agonist cannabinoids, CP 55, 940
Quantity 2 Vials of Cells
Target Entry CNR1
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