missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Lines and Blood Products
  4. Cell Lines and Cell Cultures
  5. General Cell Lines and Cell Cultures
  6. 17305299

DiscoverX Ready-to-Assay™ α2B Adrenergic Receptor Frozen Cells

Product Code. 17305299
Encompass
Click to view available options
Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17305299

Brand: DiscoverX HTS157LRTA

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

The Ready-to-Assay™ α2B Adrenergic Receptor Frozen Cells measure ADRA2B (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ α2B Adrenergic Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. [ligand]) based activation of ADRA2B GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress ADRA2B alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of ADRA2B , the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry α2B
For Use With (Application) Frozen Cells
Primary Agonist epinephrine and norepinephrine
Quantity 2 Vials of Cells
Target Entry ADRA2B
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.