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Tocris Bioscience™ AM 6545
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Product Code. 18799738
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18799738 10 mg 10mg
18718808 50 mg 50mg
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Product Code. 18799738

Brand: Tocris Bioscience™ 5443/10

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This item is not returnable. View return policy

Description

High affinity and selective CB1 antagonist

AM 6545 is a high affinity and selective CB1 antagonist (Ki = 3.3 nM). Exhibits >100-fold selectivity for CB1 over CB2 receptors. Improves glucose homeostasis, reverses hepatic steatosis and reduces body weight in diet-induced obese mice. Orally available and non-brain penetrant.
TRUSTED_SUSTAINABILITY

Spécification

Chemical Name or Material AM 6545
CAS 1245626-05-4
Synonym 5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide
Quantity 10 mg
Solubility Soluble to 20mM in DMSO
Molecular Formula C26H23Cl2N5O3S
Formula Weight 556.46
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

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