missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18761348

Tocris Bioscience™ (R)-2-Hydroxyglutaric acid disodium salt, Tocris Bioscience™
GREENER_CHOICE

Product Code. 18761348
Change view
Click to view available options
Quantity:
50 mg
Unit Size:
50mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18761348 50 mg 50mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 18761348 Supplier Tocris Bioscience™ Supplier No. 6124/50

Please to purchase this item. Need a web account? Register with us today!

148.80 EUR valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
This item is not returnable. View return policy

Description

KDM4A inhibitor; also NF-κB activator

(R)-2-Hydroxyglutaric acid disodium salt is an oncometabolite produced by mutant isocitrate dehydrogenase 1 (IDH1) and IDH2. Inhibits KDM4A in murine embryonic fibroblasts resulting in activation of mTOR. Also activates NF-κB in bone marrow stromal cells and inhibits FTO (mRNA N6-methyladenine demethylase).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (R)-2-Hydroxyglutaric acid disodium salt
CAS 103404-90-6
Synonym (R)-2-Hydroxypentanedioic acid disodium salt
Quantity 50 mg
Solubility Soluble to 100mM in water
Molecular Formula C5H6Na2O5
Formula Weight 192.08
Physical Form Solid
Color White
Product Type Bioactive Small Molecule

For Research Use Only.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.