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  7. Quinine hemisulfate monohydrate, 98+%, Thermo Scientific Chemicals

Quinine hemisulfate monohydrate, 98+%, Thermo Scientific Chemicals

Catalog Number 11448896
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Quantity:
10 g
50 g
250 g
6119-70-6
C40H54N4O10S
782.95
MFCD00150790
ZHNFLHYOFXQIOW-OIGVVMIYNA-N
Quinine sulfate (2:1) (salt) dihydrate; Quinine sulfate dihydrate
134129495
(R)-[(2R,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;tetrahydrate
O.O.OS(O)(=O)=O.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C
6119-70-6
C40H54N4O10S
782.95
MFCD00150790
ZHNFLHYOFXQIOW-OIGVVMIYNA-N
Quinine sulfate (2:1) (salt) dihydrate; Quinine sulfate dihydrate
134129495
(R)-[(2R,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;tetrahydrate
O.O.OS(O)(=O)=O.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C

Description

Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Solubility
Soluble in a mixture of chloroform and absolute alcohol (2:1).

Notes
Light sensitive. Incompatible with strong oxidizing agents, alkalis, ammonia, strong bases and iodine.
TRUSTED_SUSTAINABILITY
Melting Point 217°C to 218°C (decomposition)
Odor Odorless
Quantity 10 g
Beilstein 6113937
Sensitivity Light sensitive
Merck Index 14,8061
Solubility Information Soluble in a mixture of chloroform and absolute alcohol (2:1).
Optical Rotation −241° (c=2 in 0.1M HCl)
Formula Weight 391.47 (373.46 Anhydrous)
Percent Purity 99%
Chemical Name or Material Quinine hemisulfate monohydrate
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