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PRIMA-1, Tocris Bioscience™

Product Code. 18085132
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Product Code. 18085132 Supplier Tocris Bioscience Supplier No. 1862/10

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Description

Restores mutant p53 activity; induces apoptosis

Selectively restores mutant p53 activity in tumor cells via activation of Bax and PUMA. Induces apoptosis and inhibits growth of tumors with mutant p53.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 5608-24-2
Molecular Formula C9H15NO3
Molecular Weight (g/mol) 185.223
InChI Key RFBVBRVVOPAAFS-UHFFFAOYSA-N
Synonym prima-1, 2,2-bis hydroxymethyl-1-azabicyclo 2,2,2, octan-3-one, 2,2-bis hydroxymethyl-1-azabicyclo 2.2.2 octan-3-one, 2,2-bis hydroxymethyl-3-quinuclidinone, p53 reactivation and induction of massive apoptosis, 2,2-bishydroxymethyl-1-aza-bicyclo 2.2.2 octan-3-one, 2,2-bis hydroxymethyl-1-azabicyclo 2,2,2 octan-3-one, prima 1, tocris-1862, prima 1;prima1
PubChem CID 322968
IUPAC Name 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one
SMILES C1CN2CCC1C(=O)C2(CO)CO

Specifications

Quantity 10 mg
Formula Weight 185.22
Percent Purity >99%
Chemical Name or Material PRIMA-1
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