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Prednisone, 98%, Thermo Scientific Chemicals

Product Code. 13458638 Shop All Thermo Scientific Chemicals Products
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Quantity:
5 g
25 g
Packaging:
Glass bottle
Unit Size:
25g
5g
This item is not returnable. View return policy

Product Code. 13458638

Brand: Thermo Scientific Acros 448950050

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Prednisone, 98%, CAS # 53-03-2, is a synthetic glucocorticoid with anti-inflammatory, immunomodulatory, antineoplastic, and adrenergic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities

• It shows antineoplastic and adrenergic activities against hormone-sensitive cancer cells

• This compound binds to its receptors and enters the nucleus activating specific nuclear receptors, resulting in an altered gene expression and inhibiting proinflammatory cytokine production

Applications

• Prednisone can reduce circulating lymphocytes, promote cell differentiation, and stimulate apoptosis in sensitive tumor cell lines

• It is considered a prodrug that is converted by the liver into prednisolone which is the active steroid compound

• It is also used in some studies to investigate the effects of daily administration of MIDD0301, on the animal and organs weights and hematological profile

TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 53-03-2
Molecular Formula C21H26O5
Molecular Weight (g/mol) 358.434
InChI Key XOFYZVNMUHMLCC-ZPOLXVRWSA-N
Synonym prednisone, deltasone, dehydrocortisone, decortin, meticorten, orasone, prednison, rectodelt, ultracorten, dacortin
PubChem CID 5865
ChEBI CHEBI:8382
IUPAC Name (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C

Spezifikation

Assay Percent Range 98%
Packaging Glass bottle
Quantity 5 g
Formula Weight 358.43
Chemical Name or Material Prednisone
compliance-icons
Produktidentifikator
  • Prednisone
Signalwort
  • Warning
Gefahrenkategorie
  • Reproductive toxicity Category 2
Gefahrenhinweis
  • H361-Suspected of damaging fertility or the unborn child.
Sicherheitshinweis
  • P201-Obtain special instructions before use.
  • P202-Do not handle until all safety precautions have been read and understood.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only

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