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  5. STEMCELL Technologies Perhexiline Maleate

STEMCELL Technologies Perhexiline Maleate

Product Code. 17119991
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Quantity:
1 mg
5 mg
Unit Size:
1mg
5mg
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Product Code. 17119991

Brand: STEMCELL Technologies 1000267

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This item is not returnable. View return policy

Description

Carnitine palmitoyltransferase 1 (CPT1) and CPT2 inhibitor

  • Perhexiline Maleate is an inhibitor of the mitochondrial enzymes carnitine palmitoyltransferase 1 (CPT1; IC50 = 0.077 mM in rat heart; IC50 = 0.148 mM in rat liver) and CPT2 (IC50 = 0.079 mM in rat heart; Kennedy et al. 1996; Kennedy et al.) 2000)
  • Perhexiline Maleate also modulates autophagy via mammalian target of rapamycin complex 1 (mTORC1) signaling (Balgi et al.)
  • Alters myocardial metabolism from fatty acid to glucose utilization, resulting in higher ATP production and oxygen consumption (Ashrafian et al.; Jeffrey et al.)
  • Inhibits mTORC1 signaling and induces autophagy in MCF-7 cells (Balgi et al.)

Specifications

CAS 6724-53-4
Quantity 1 mg
Molecular Formula C19H35N · C4H4O4
Purity ≥95%
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