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DiscoverX PathHunter™ U2OS TORC3 Nuclear Translocation Cell Line

Product Code. 17334399
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Quantity:
2 Vials
Unit Size:
2 ampoules
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17334399 2 Vials 2 ampoules
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Product Code. 17334399 Supplier DiscoverX Supplier No. 931120C3

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Description

The PathHunter™ U2OS TORC3 Nuclear Translocation Cell Line measures CRTC/CREB pathway activation via nuclear translocation of TORC3. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS TORC3 Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the CRTC/CREB pathway. This cell line enables assessment of ligand (e.g. forskolin) based pathway activation via detection of resulting TORC3 (CRTC3) nuclear translocation. This product uses EFC technology. The included cell line overexpresses PL-tagged TORC3 (CRTC3) and nuclear localized EA. Upon pathway activation, induced nuclear translocation of TORC3 leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry TORC3 (CRTC3) nuclear translocation
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist Forskolin
Quantity 2 Vials
Target Entry TORC3 (CRTC3)
Accession Number NM_022769.4
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