missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Lines and Blood Products
  4. Cell Lines and Cell Cultures
  5. General Cell Lines and Cell Cultures
  6. 17394169

DiscoverX PathHunter™ U2OS RANK-IκB Functional Assay

Product Code. 17394169
Encompass
Click to view available options
Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17394169

Brand: DiscoverX 930994C3

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

The PathHunter™ U2OS RANK-IκB Functional Assay measures pathway activation-induced degradation of IκB target protein. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS RANK-IκB Functional Assay is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting the NFκB pathway. This cell line enables detection of IκB levels, allowing for assessment of NFκB pathway activation-induced IκB degradation. This product uses EFC technology. The cell line included overexpresses IκB target protein fused to PL alongside untagged RANK. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of IκB EFC signal is lost. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry NFκB pathway activation-induced IκB degradation
Cell Line U2OS
Format 2 vials
For Use With (Application) Cell Lines
Primary Agonist sRANKL
Quantity 2 Vials
Target Entry RANK-IκB
Accession Number NM_003839.3
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.