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DiscoverX PathHunter™ U2OS LEPR/LEPR Dimerization Cell Line

Product Code. 17334389
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Quantity:
2 Vials
Unit Size:
2 ampoules
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17334389 2 Vials 2 ampoules
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Product Code. 17334389 Supplier DiscoverX Supplier No. 931107C3

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Description

The PathHunter™ U2OS LEPR/LEPR Dimerization Cell Line measures ligand-induced dimerization of LEPR/LEPR . This cell line ships as two vials of cryopreserved cells.

The PathHunter™ LEPR/LEPR Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. leptin) induced dimerization of LEPR/LEPR receptors. This product uses EFC technology. The cell line included overexpresses LEPR target protein fused to PK alongside LEPR target protein fused to EA. Upon ligand-induced dimerization of LEPR/LEPR , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Dimerization
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist Leptin
Quantity 2 Vials
Target Entry LEPR/LEPR
Accession Number NM_002303.5
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