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DiscoverX PathHunter™ U2OS CSF1R/CSF1R Dimerization Cell Line

Product Code. 17334329
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Quantity:
2 Vials
Unit Size:
2 ampoules
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17334329 2 Vials 2 ampoules
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Product Code. 17334329 Supplier DiscoverX Supplier No. 931061C3

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Description

The PathHunter™ U2OS CSF1R/CSF1R Dimerization Cell Line measures ligand-induced dimerization of CSF1R/CSF1R . This cell line ships as two vials of cryopreserved cells.

The PathHunter™ CSF1R/CSF1R Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. M-CSF) induced dimerization of CSF1R/CSF1R receptors. This product uses EFC technology. The cell line included overexpresses CSF1R target protein fused to PK alongside CSF1R target protein fused to EA. Upon ligand-induced dimerization of CSF1R/CSF1R , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Dimerization
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist M-CSF
Quantity 2 Vials
Target Entry CSF1R/CSF1R
Accession Number NM_005211.3
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