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DiscoverX PathHunter™ U2OS ACVR1B/BMPR2 Dimerization Cell Line

Product Code. 17304349
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17304349

Brand: DiscoverX 931072C3

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This item is not returnable. View return policy

Description

The PathHunter™ U2OS ACVR1B/BMPR2 Dimerization Cell Line measures ligand-induced dimerization of ACVR1B/BMPR2 . This cell line ships as two vials of cryopreserved cells.

The PathHunter™ ACVR1B/BMPR2 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. activin A) induced dimerization of ACVR1B/BMPR2 receptors. This product uses EFC technology. The cell line included overexpresses ACVR1B target protein fused to PK alongside BMPR2 target protein fused to EA. Upon ligand-induced dimerization of ACVR1B/BMPR2 , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Dimerization
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist Activin A
Quantity 2 Vials
Target Entry ACVR1B/BMPR2
Accession Number NM_004302.4
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