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DiscoverX PathHunter™ PTH Bioassay Kit

Product Code. 17362969
Encompass
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Quantity:
1,000 dp (10 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17362969

Brand: DiscoverX 930315Y200048

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This item is not returnable. View return policy

Description

The PathHunter™ PTH Bioassay Kit measures PTHR (GPCR) activity via recruitment of β-Arrestin2. Bioassay kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ PTH Bioassay kit provides an easy-to-use cell based assay to determine parathyroid hormone potency and detect neutralizing antibodies. This bioassay assesses PTH based activation of PTHR GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged PTHR and EA-tagged β-Arrestin 2. Activation of PTHR stimulates the recruitment of β-Arrestin 2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.

Specifications

Assay Entry β-Arrestin recruitment
For Use With (Application) Assay-Ready Bioassay Kits
Quantity 1,000 dp (10 x 96-well)
Target Entry PTHR
Cell Line CHO-K1
Target PTHR
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