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DiscoverX PathHunter™ Jurkat NFAT Pathway Reporter Cell Line

Product Code. 17324419
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17324419

Brand: DiscoverX 931141C19

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This item is not returnable. View return policy

Description

The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line measures NFAT pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting the NFAT pathway. This cell line enables assessment of NFAT pathway stimulation based on changes in the expression of a NFAT response element-driven reporter protein. This product uses EFC technology. The included cell line expresses PL-tagged reporter protein under the control of a NFAT pathway-inducible transcriptional response element. Pathway activation induces expression of the PL-tagged protein, allowing detection of EFC signal upon addition of EA-containing detection reagent. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry NFAT pathway stimulation
Cell Line Jurkat
For Use With (Application) Cell Lines
Primary Agonist Anti-CD3 antibody [OKT3]
Quantity 2 Vials
Target Entry NFAT
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