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DiscoverX PathHunter™ HEK 293 IL3RA/CD131 Dimerization Cell Line

Product Code. 17314129
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17314129

Brand: DiscoverX 930969C1

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This item is not returnable. View return policy

Description

The PathHunter™ HEK 293 IL3RA/CD131 Dimerization Cell Line measures ligand-induced dimerization of IL3RA/CD131 . This cell line ships as two vials of cryopreserved cells.

The PathHunter™ IL3RA/CD131 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-3) induced dimerization of IL3RA/CD131 receptors. This product uses EFC technology. The cell line included overexpresses IL3RA target protein fused to PK alongside CD131 target protein fused to EA. Upon ligand-induced dimerization of IL3RA/CD131 , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Dimerization
Cell Line 293H
For Use With (Application) Cell Lines
Primary Agonist IL-3
Quantity 2 Vials
Target Entry IL3RA/CD131
Accession Number NM_002183.2
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