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DiscoverX PathHunter™ CHO-K1 mPTGIR β-Arrestin Cell Pool
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Quantity:
2 Vials
Unit Size:
2 ampoules
Description
The PathHunter™ mPTGIR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin I2, beraprost) based activation of mPTGIR GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged mPTGIR and EA-tagged β-Arrestin 2. Activation of mPTGIR stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable cell pool is provided as two vials of cryopreserved cells. Please note that this product expresses the mouse version of this protein.
Specifications
Specifications
| Assay Entry | β-Arrestin recruitment |
| Cell Line | CHO-K1 |
| For Use With (Application) | Cell Pools |
| Quantity | 2 Vials |
| Target Entry | mPTGIR |
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