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DiscoverX PathHunter™ CHO-K1 mGLP1R β-Arrestin-1 Cell Line

Product Code. 17384129
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17384129

Brand: DiscoverX 930974C2

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This item is not returnable. View return policy

Description

The PathHunter™ CHO-K1 mGLP1R β-Arrestin-1 Cell Line measures MGLP1R (GPCR) activity via recruitment of β-Arrestin-1. This cell line ships as two vials of cryopreserved cells. Mouse protein.

The PathHunter™ mGLP1R (ARR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. exendin-4) based activation of mGLP1R GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged mGLP1R and EA-tagged β-Arrestin-1. Activation of mGLP1R stimulates the recruitment of β-Arrestin-1 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein.

Specifications

Assay Entry β-Arrestin Recruitment
Cell Line CHO-K1
Format 2 vials
For Use With (Application) Cell Lines
Primary Agonist Exendin-4
Quantity 2 Vials
Target Entry mGLP1R (ARR1)
Accession Number NM_021332
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