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DiscoverX PathHunter™ CHO-K1 mGHSR1a β-Arrestin Cell Line

Product Code. 17333519
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Quantity:
2 Vials
Unit Size:
2 ampoules
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17333519 2 Vials 2 ampoules
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Product Code. 17333519 Supplier DiscoverX Supplier No. 930605C2

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Description

The PathHunter™ CHO-K1 mGHSR1a β-Arrestin Cell Line measures mGHSR1a (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells. Mouse protein.

The PathHunter™ mGHSR1a β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. grehlin) based activation of mGHSR1a GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged mGHSR1a and EA-tagged β-Arrestin 2. Activation of mGHSR1a stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein.

Specifications

Assay Entry β-Arrestin recruitment
Cell Line CHO-K1
For Use With (Application) Cell Lines
Primary Agonist Ghrelin
Quantity 2 Vials
Target Entry mGHSR1a
Accession Number NM_177330
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