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DiscoverX PathHunter™ CHO-K1 mCCR9 β-Arrestin Cell Line

Product Code. 17363729
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17363729

Brand: DiscoverX 930734C2

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This item is not returnable. View return policy

Description

The PathHunter™ CHO-K1 mCCR9 β-Arrestin Cell Line measures mCCR9 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells. Mouse protein.

The PathHunter™ mCCR9 β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL25) based activation of mCCR9 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged mCCR9 and EA-tagged β-Arrestin 2. Activation of mCCR9 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein.

Specifications

Assay Entry β-Arrestin recruitment
Cell Line CHO-K1
For Use With (Application) Cell Lines
Primary Agonist CCL25 (murine)
Quantity 2 Vials
Target Entry mCCR9
Accession Number NM_009913.6
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