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DiscoverX PathHunter™ BHK-21 rPTGER4 β-Arrestin Cell Line

Product Code. 17303999
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Quantity:
2 Vials
Unit Size:
2 ampoules
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Product Code. Quantity unitSize
17303999 2 Vials 2 ampoules
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Product Code. 17303999 Supplier DiscoverX Supplier No. 930908C16

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Description

The PathHunter™ BHK-21 rPTGER4 β-Arrestin Cell Line measures rPTGER4 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells. Rat protein.

The PathHunter™ rPTGER4 β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. [ligand]) based activation of rPTGER4 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged rPTGER4 and EA-tagged β-Arrestin2. Activation of rPTGER4 stimulates the recruitment of β-Arrestin2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein.

Specifications

Assay Entry β-Arrestin Recruitment
Cell Line BHK-21
For Use With (Application) Cell Lines
Primary Agonist Prostaglandin E2
Quantity 2 Vials
Target Entry rPTGER4
Accession Number NM_032076
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