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p65/RELA Mouse anti-Human, Rat, Clone: 1B12D11, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66535-1-IG-150UL
Additional Details : Weight : 0.00010kg
Description
This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.Specifications
p65/RELA | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q04206 | |
Rela | |
p65; RELA Fusion Protein Ag1199 | |
150 μL | |
Primary | |
Human, Rat | |
Antibody | |
IgG1 |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
1B12D11 | |
Unconjugated | |
RELA | |
NFKB3, p65, RELA, Transcription factor p65 | |
Mouse | |
Protein G | |
RUO | |
309165, 5970 | |
-20°C | |
Liquid |