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Tocris Bioscience™ NSC 74859
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Product Code. 30001646
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30001662 50 mg 50mg
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Product Code. 30001646 Supplier Tocris Bioscience™ Supplier No. 4655/10

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Description

Selective STAT3 inhibitor

NSC 74859 selectively inhibits STAT3 DNA-binding activity in vitro (IC50 values are 86, 160, and >300 μM for STAT3-STAT3, STAT1-STAT3 and STAT1-STAT1 DNA-binding activity respectively). NSC 74859 blocks growth and induces apoptosis preferentially in tumor cells that contain persistently active STAT3 in vitro and arrests tumor growth in a murine xenograft model in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 501919-59-1
Molecular Formula C16H15NO7S

Specifications

Quantity 10 mg
Formula Weight 365.36
Purity >98%
Molecular Weight (g/mol) 365.356
Chemical Name or Material NSC 74859
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