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  5. Tocris Bioscience™ NIBR LTSi

Tocris Bioscience™ NIBR LTSi

Product Code. 30226374
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30226374

Brand: Tocris Bioscience™ 8175/50

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This item is not returnable. View return policy

Description

Potent and selective LATS inhibitor; activates YAP signaling

NIBR-LTSi is a potent and selective large tumor suppressor kinase (LATS) inhibitor (IC50 = 1.4 nM). Also activates YAP signaling (EC50 = 1.0 - 2.7 μM). Promotes liver organoid formation (EC50 = 0.35 μM), hepatocyte proliferation, ISC expansion, and blocks differentiation. NIBR-LTSi is orally bioavailable and suitable for use in vivo and in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[4-[(3R)-Piperidin-3-yl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridin-4-amine
Quantity 50 mg
Target Other Kinase Inhibitors
Molecular Formula C18H20N4O
Purity 0.98
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