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R&D Systems™ MSC 1186

Product Code. 18784444
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18784444 50 mg 50mg
18734524 10 mg 10mg
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Product Code. 18784444 Supplier R&D Systems™ Supplier No. 7927/50
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Estimated Shipment: 30-10-2026
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Description

A Tocris product, part of R&D Systems. Potent and selective SRPK family inhibitor

MSC1186 is a potent and selective inhibitor of serine arginine protein kinases (SRPK) 3, 1 and 2 (IC50 values are 0.6 nM, 3 nM and 81 nM respectively in biochemical assay; EC50 values in NanoBRETassay are 40 nM, 98 nM and 149 nM, respectively). Shows no activity at CLK and DYRK families (IC50 >10 μM).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[3-[[[2-(6-Chloro-7-fluoro-1H-benzimidazol-2-yl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide
CAS 2871698-23-4
Quantity 50 mg
Product Line Tocris
Target SRPK3/STK23
Molecular Formula C19H17ClFN7O2S
Purity 0.98
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