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Tocris Bioscience™ MCU i4

Product Code. 18024672
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Quantity:
50 mg
Unit Size:
50mg
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Product Code. 18024672 Supplier Tocris Bioscience™ Supplier No. 7195/50

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153.00 EUR valid until 2026-03-31
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Description

Negative modulator of mitochondrial Ca2+ uniporter (MCU)

MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex, which binds to MICU1, a regulatory protein within MCU complex. MCU i4 reduces mitochondrial Ca2+ uptake in multiple cell lines including MEFs, MDA-MB,231 and HEK293T cells, and demonstrates a negative effect on mitochondrial membrane potential. In ex vivo muscle fibres, MCU i4 reduces mitochondrial Ca2+ uptake and impairs muscle cell growth.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 4-[[4-(Diethylamino)phenyl]amino]-6-methyl-3-quinolinecarboxylic acid ethyl ester
CAS 371924-24-2
Quantity 50 mg
Target Mitochondrial Calcium Uniporter Inhibitors
Molecular Formula C23H27N3O2
Purity 98%
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