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Tocris Bioscience™ Mandi

Product Code. 18777726
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10 mg
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10mg
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Product Code. 18777726 Supplier Tocris Bioscience™ Supplier No. 7681/10

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Description

Highly efficient chemical inducer of proximity (CIP)

Mandi is a chemical inducer of proximity (CIP) in vivo and in vitro (EC50 = 0.43 μM in a luciferase gene expression assay). Mandi induces complex formation between PYR1Mandi, a mutant of Abscisic Acid (Cat. No. 6554) receptor PYR1, and Abscisic Acid insensitive (ABI). Mandi may be used to induce protein colocalization and interaction. It is non-toxic, orthogonal to mammalian processes and other CIPs, and highly cell permeable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 4-Chloro-N-[2-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]ethyl]-α-(2-propyn-1-yloxy)benzeneacetamide
CAS 374726-62-2
Quantity 10 mg
Target Protein Dimerizers
Molecular Formula C23H22ClNO4
Purity 0.98
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