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  5. Tocris Bioscience™ LSN 2463359

Tocris Bioscience™ LSN 2463359
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Product Code. 18781088
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18781088

Brand: Tocris Bioscience™ 5275/50

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This item is not returnable. View return policy

Description

Potent and selective positive allosteric modulator at mGlu5

LSN 2463359 is a potent and selective positive allosteric modulator at the mGlu5 receptor (EC50 = 24 nM). Has no activity at mGlu1-4, mGlu8 and GABAB receptors. Reverses methylazoxymethanol acetate (MAM)-induced deficits in reversal learning memory and normalizes SDZ 220-581 and RO 63-1908 -induced alterations in instrumental responses in rat models. Promotes wakefulness in vivo. Brain penetrant and orally active.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 50 mg
Product Type LSN 2463359
Purity >99%
Molecular Weight (g/mol) 265.31
Inhibitors LSN 2463359

For Research Use Only

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