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LG 100268, Tocris Bioscience™

Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers
Brand: Tocris Bioscience 5920/25
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Description
LG 100268 is a potent and selective retinoid X receptor (RXR) agonist (EC50 = 4 nM). Displays >1000-fold selectivity for RXR over RAR. Activates RXR homodimers to induce transcriptional activation. Induces tissue transglutaminase (TGase) activity in HL-60 human promyelocytic leukemia cell line. Also activates RXR/PPARγ heterodimers.Specifications
| 6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic acid | |
| 153559-76-3 | |
| >98% | |
| 25 mg |
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