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R&D Systems™ KL 465
Description
KL 465 is a MAGE-A3 Degrader (PROTAC™) (DC50 = 2 μM; Dmax = 60%). MAGE-A3 degradation with KL 465 decreases cancer cell viability and is VHL dependent. PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.
Specifications
Specifications
| Chemical Name or Material | (2S,4R)-N-(2-(2-(2-(2-((4-(Furan-2-carbonyl)piperazin-1-yl)methyl)-4-(1H-indazol-4-yl)phenoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide |
| CAS | 3057446-82-6 |
| Quantity | 5 mg |
| Product Line | Tocris |
| Target | Active Degraders |
| Molecular Formula | C56H60N8O9S |
| Purity | 0.98 |
Product Title
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