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Kaempferol, 98+%, Thermo Scientific Chemicals
Description
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.
Solubility
Soluble in DMSO or ethanol to 100mM
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep away fom strong oxidizing agents.
Specifications
Specifications
| Melting Point | 276°C to 278°C |
| Color | Yellow |
| Quantity | 50 mg |
| Beilstein | 304401 |
| Merck Index | 14,5274 |
| Solubility Information | Soluble in DMSO or ethanol to 100mM |
| IUPAC Name | 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| Formula Weight | 286.24 |
| Percent Purity | ≥98% |
| Physical Form | Powder |
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RUO – Research Use Only
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