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Tocris Bioscience™ IP7e
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Product Code. 18712699
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Product Code. 18712699 Supplier Tocris Bioscience™ Supplier No. 5699/10

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Potent Nurr1 activator

IP7e is a potent Nurr1 activator (EC50 = 3.9 nM). Delays onset and reduces severity of symptoms in mice with experimental autoimmune encephalomyelitis (EAE). Also suppresses NF-κB signaling. Brain penetrant and orally bioavailable.
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Specifications

Chemical Name or Material 6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one
CAS 500164-74-9
Quantity 10 mg
Target NFkB/IkB Inhibitors
Molecular Formula C23H22N2O4
Formula Weight 390.43
Purity >98%
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