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Tocris Bioscience™ IKK 16
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Product Code. 18035042
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18035042 50 mg 50mg
18026062 10 mg 10mg
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Product Code. 18035042 Supplier Tocris Bioscience™ Supplier No. 2539/50

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Selective inhibitor of IKK

Selective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). Inhibits TNF-α-stimulated IκB degradation and expression of adhesion molecules E-selectin, ICAM and VCAM (IC50 values are 1.0, 0.5, 0.3 and 0.3 μM respectively). Inhibits LPS-induced TNF-α release in vivo and neutrophil extravasion in thioglycollate-induced peritonitis.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1186195-62-9
Molecular Formula C28H30ClN5OS

Specifications

Quantity 50 mg
Formula Weight 520.09
Purity >98%
Molecular Weight (g/mol) 520.092
Chemical Name or Material IKK 16
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