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Tocris Bioscience™ IKK 16

Description
Selective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). Inhibits TNF-α-stimulated IκB degradation and expression of adhesion molecules E-selectin, ICAM and VCAM (IC50 values are 1.0, 0.5, 0.3 and 0.3 μM respectively). Inhibits LPS-induced TNF-α release in vivo and neutrophil extravasion in thioglycollate-induced peritonitis.
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 520.09 |
| Purity | >98% |
| Molecular Weight (g/mol) | 520.092 |
| Chemical Name or Material | IKK 16 |
Product Title
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