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IFN-γ Mouse anti-Human, PE, Clone: 4S.B3, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 561056
Additional Details : Weight : 0.01000kg
Description
The 4S.B3 monoclonal antibody specifically binds to interferon-γ(IFN-γ). The immunogen used to generate this hybridoma was partially purified human IFN-γobtained from supernatants of human PBMC stimulated with Staphylococcus aureus . Interferon-γ(IFN-γ) is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ + T cells. IFN- γexerts its biological effects through specific binding to the high-affinity IFN-γReceptor Complex comprised of IFN-γRα (CD119) and ese influences can involve IFN- γ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells themselves. Human IFN-γis a 14- 18 kDa glycoprotein containing 143 amino acid residues.
Specifications
| IFN-γ | |
| Monoclonal | |
| 0.2mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Human IFN-γ from supernatants of S. aureus-stimulated PBMC | |
| 25 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 4S.B3 | |
| PE | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
For Research Use Only.