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Tocris Bioscience™ ICG 001

Product Code. 18065922
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18035112 50 mg 50mg
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Product Code. 18065922 Supplier Tocris Bioscience™ Supplier No. 4505/10

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291.60 EUR valid until 2026-03-31
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Description

Inhibits TCF/β-catenin-mediated transcription

ICG 001 is an inhibitor of TCF/β-catenin-mediated transcription. Selectively inhibits β-catenin/CBP interaction; displays no effect on β-catenin/p300 interaction. Exhibits growth inhibitory effects in colon carcinoma cell lines (SW480 and HCT-116 cells); also displays efficacy in Min mouse and nude mouse SW620 xenograft models.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
CAS 780757-88-2
Quantity 10 mg
Target beta-Catenin Inhibitors
Molecular Formula C33H32N4O4
Purity 0.98
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