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Thermo Scientific™ Hypersil™ PREP BDS C8 HPLC Columns
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Scale up to prep LC using Hypersil PREP C8 BDS HPLC columns which offers selectivity similar to C18 but with reduced retention in analytical and preparative scale.
Scale up from analytical to a preparative LC method with Thermo Scientific™ Hypersil™ PREP BDS C8 reversed phase preparative HPLC column. Our columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. With similar selectivity to C18 columns and predictable elution order, C8 columns with base deactivation for reduced silanol activity are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations.
Similar selectivity, less retention than C18 columns
- Successful retention and separation of moderately hydrophobic analytes.
- Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns.
- Base deactivated silica.
- C8 (USP L7) selectivity.
- pH stable from 2 to 8.
- Maximum temperature of 60°C.
Faster separations
- Higher analytical throughput compared to C18 alkyl chain chemistry.
- Quicker compound elution due to reduced hydrophobic interactions.
Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.
Standard Threaded and Standard Flange Hardware
- Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
- Standard threaded hardware for column i.d. < 40mm.
- Standard flange hardware for column i.d. ≥ 40mm.
- Standard hardware can be modified on request to be compatible with SFC.
XtendedLife Hardware
- Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
- Compatible with SFC and is available in dimensions up to 50mm i.d.
Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.
Customer Specific Orders
- If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
- Please contact your local sales representative for Customer Specific Orders.
- Custom built columns are not eligible for returns.
Tekniske data
Tekniske data
| Column Format | Preparative Column, Xtended Life |
| Diameter (Metric) | 50 mm |
| Length (Metric) | 250 mm |
| Max. Pressure | 2000 psi (140 bar) |
| Particle Size | 5 μm |
| pH | 2 to 8 |
| Pore Size | 145 Å |
| Surface Area | 185 m²/g |
| Temperature | 60°C |
| USP Type | L7 |
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