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Abnova™ Human PLN Partial ORF (AAH05269, 1 a.a. - 30 a.a.) Recombinant Protein with GST-tag at N-terminal
Used for AP, Array, ELISA, WB-Re
Brand: Abnova™ H00005350-Q01.25ug
Additional Details : Weight : 0.00010kg
Description
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]
Sequence: MEKVQYLTRSAIRRASTIEMPQQARQKLQNSpecifications
AAH05269 | |
50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer. | |
28.93kDa | |
12.5% SDS-PAGE Stained with Coomassie Blue. | |
MEKVQYLTRSAIRRASTIEMPQQARQKLQN | |
RUO | |
PLN | |
Wheat Germ (in vitro) | |
GST | |
Liquid |
Antibody Production, ELISA, Protein Array, Western Blot | |
5350 | |
PLN (Human) Recombinant Protein (Q01) | |
25 ug | |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. | |
CMD1P/PLB | |
PLN | |
Recombinant | |
wheat germ expression system |