Thermo Scientific™ anti-Interleukin 6 Recombinant

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
Host Species: E. Coli
Cross Reactivity: Not Applicable
Formulation: 1 Vial purified Protein (1 ng/ml) in 4% BSA and no preservative;

PA5-32691 detects CAV1/Caveolin in Human samples. PA5-32691 has been successfully used in Immunohistochemistry (Paraffin) procedures. PA5-32691 The immunogen is Synthetic 16 amino acid peptide from N-terminus of human CAV1/Caveolin..