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ACROBiosystems Human CD30 / TNFRSF8 Protein, His Tag
MALS verified
POA
Specifications
| Accession Number | NP_001234.2 |
|---|---|
| Molecular Weight (g/mol) | 39.3 kDa |
| Source | Human CD30, His Tag (CD0-H5229) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2). |
| Immunogen | Phe 19 - Lys 379 |
| Storage Requirements | -20°C |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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15816127
|
ACROBiosystems
CD0-H5229-100UG |
100 µg |
This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on +351 21 425 33 50 for assistance |
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15826127
|
ACROBiosystems
CD0-H5229-1MG |
1 mg |
This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on +351 21 425 33 50 for assistance |
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Description
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.3 kDa. The protein migrates as 53-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_001234.2 | |
| Human CD30, His Tag (CD0-H5229) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2). | |
| -20°C | |
| CD30 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |
| 39.3 kDa | |
| Phe 19 - Lys 379 | |
| TNFRSF8,CD30,D1S166E,Ki-1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |