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Guanosine-5'-Triphosphate Disodium Salt, MP Biomedicals™

Código de producto. 11457800 Tienda MP Biomedicals Productos
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100 mg
Tamaño de la unidad:
100mg
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Código de producto. 11457800 Proveedor MP Biomedicals N.º de proveedor 0210071080
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Estimated Shipment: 09-03-2027
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Descripción

Required as a coenzyme for protein biosynthesis in a cell-free system. Guanosine-5'-Triphosphate Disodium Salt, MP Biomedicals (GTP) is a purine nucleotide that functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy

GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

GTP is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exchange factors (GEF).

Especificaciones

CAS 56001-37-7
Physical Form Powder
Quantity 100 mg
Molecular Formula C10H14N5Na2O14P3
MDL Number MFCD03410297
Synonym guanosine 5'-triphosphate, guanosine-5'-triphosphate disodium salt dihydrate gtp, guanosine-triphosphate, guanosine 5'-triphosphate 4-, gtp 4-, 2r,3s,4r,5r-5-2-amino-6-hydroxy-9h-purin-9-yl-3,4-dihydroxyoxolan-2-yl methyl phosphonato oxy phosphonatooxy phosphinate, 2r,3s,4r,5r-5-2-amino-6-oxo-3h-purin-9-yl-3,4-dihydroxyoxolan-2-yl methoxy-oxidophosphoryl oxy-oxidophosphoryl phosphate
Solubility Information Soluble in water (50mg/mL - clear and colorless).
InChI Key FIZIYLKEXVIRHJ-KHRSEZDTNA-L
SMILES [Na+].[Na+].NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
IUPAC Name disodium;(2R,3R,4S,5R)-2-(2-amino-6-oxo-3H-purin-9-yl)-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolane-3,4-diolate
Molecular Weight (g/mol) 567.14
PubChem CID 131676145
Formula Weight 567.2
Percent Purity ≥98%
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Seguridad y manipulación

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Nombre del producto
  • GUANOSINE-5`-TRIPHOSPHATE DISODIUM SALT
 Palabra de advertencia
  • Warning
 Clasificación
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Indicaciones de peligro
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Consejos de prudencia
  • P101-If medical advice is needed, have product container or label at hand.
  • P102-Keep out of reach of children.
  • P103-Read label before use.
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321-Specific treatment (see on this label).
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Otros peligros
  • MIXTURE LIST-Contain: guanosine 5'-(disodium dihydrogentriphosphate)
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