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GSTM3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA557191
Additional Details : Weight : 0.02000kg
Description
Immunogen sequence: TYDILDQNRI FDPKCLDEFP NLKAFMCRFE ALEKIAAYLQ SDQFCKMPIN N Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 86%.
Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme which in humans is encoded by theGSTM3 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13. 3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.Specifications
GSTM3 | |
Polyclonal | |
Unconjugated | |
GSTM3 | |
brain GST; brain type mu-glutathione S-transferase; Fsc2; glutathione S-alkyltransferase M3; glutathione S-aralkyltransferase M3; glutathione S-aryltransferase M3; glutathione S-transferase GT9.3; glutathione S-transferase M3 (brain); glutathione S-transferase Mu 3; glutathione S-transferase mu 3 (brain); glutathione S-transferase, mu 3; glutathione S-transferase, Mu-3; GST class-mu 3; GST5; GSTB; GSTM3; GSTM3-3; GTM3; hGSTM3-3; mGSTM5; S-(hydroxyalkyl)glutathione lyase M3 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
2947 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
P21266 | |
GSTM3 | |
Recombinant protein corresponding to Human GSTM3 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only