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  5. Glycine ethyl ester hydrochloride, 99%

Glycine ethyl ester hydrochloride, 99%

Product Code. 11484073
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Product Code. 11484073 Supplier Thermo Scientific Alfa Aesar Supplier No. A10315.22
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Description

CAS: 623-33-6 | C4H10ClNO2 | 139.579 g/mol

Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.

Solubility
Soluble in water (>1000 mg/ml at 20°C), ethanol, DMSO, and methanol.

Notes
Hygroscopic. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 623-33-6
Molecular Formula C4H10ClNO2
Molecular Weight (g/mol) 139.579
MDL Number MFCD00012871
InChI Key TXTWXQXDMWILOF-UHFFFAOYSA-N
Synonym glycine ethyl ester hydrochloride, ethyl glycinate hydrochloride, ethyl 2-aminoacetate hydrochloride, h-gly-oet.hcl, glycine, ethyl ester, hydrochloride, ethyl aminoacetate hydrochloride, glycine hydrochloride ethyl ester, amino-acetic acid ethyl ester hydrochloride, glycine ethyl ester hydrochloric acid, glycineethylesterhydrochlor
PubChem CID 2723640
IUPAC Name ethyl 2-aminoacetate;hydrochloride
SMILES CCOC(=O)CN.Cl

Specifications

Melting Point 144°C to 148°C
Beilstein 3594034
Solubility Information Soluble in water (>1000mg/ml at 20°C),ethanol,DMSO,and methanol.
Quantity 100 g
Formula Weight 139.58
Sensitivity Hygroscopic
Percent Purity 99%
Chemical Name or Material Glycine ethyl ester hydrochloride

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