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  5. Tocris Bioscience™ GBR 12909 dihydrochloride

Tocris Bioscience™ GBR 12909 dihydrochloride

Product Code. 18767696
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18767696 10 mg 10mg
18728896 50 mg 50mg
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Product Code. 18767696 Supplier Tocris Bioscience™ Supplier No. 0421/10

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Description

Selective DA uptake inhibitor; also σ ligand

GBR 12909 dihydrochloride is a potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has >100-fold lower affinity for the noradrenaline and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
CAS 67469-78-7
Assay Percent Range >98%
Quantity 10 mg
Solubility Soluble to 50mM in DMSO
Molecular Formula C28H32F2N2O.2HCl
Formula Weight Observed MW: 523.49

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